Marina Ramirez-Alvarado Selected Research

Immunoglobulin Light Chains (Immunoglobulin Light Chain)

1/2020	Light chain amyloidosis induced inflammatory changes in cardiomyocytes and adipose-derived mesenchymal stromal cells.
1/2019	Mechanistic Insights into the Early Events in the Aggregation of Immunoglobulin Light Chains.
9/2018	Immunoglobulin light chain amyloid aggregation.
12/2017	Mesenchymal stromal cells protect human cardiomyocytes from amyloid fibril damage.
6/2017	Assessment of renal response with urinary exosomes in patients with AL amyloidosis: A proof of concept.
1/2017	Solid-state NMR chemical shift assignments for AL-09 VL immunoglobulin light chain fibrils.
1/2017	Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation.
1/2016	Recruitment of Light Chains by Homologous and Heterologous Fibrils Shows Distinctive Kinetic and Conformational Specificity.
1/2016	Cell Damage in Light Chain Amyloidosis: FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING.
12/2015	Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding.

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Marina Ramirez-Alvarado Research Topics

Disease

30	Amyloidosis 06/2021 - 07/2006
26	Immunoglobulin Light-chain Amyloidosis 01/2021 - 09/2008
12	Amyloid Plaque 01/2021 - 07/2006
8	Proteostasis Deficiencies 12/2017 - 01/2009
6	Multiple Myeloma 11/2017 - 01/2008
4	Alzheimer Disease (Alzheimer's Disease) 05/2012 - 07/2006
3	Neoplasms (Cancer) 12/2020 - 03/2007
2	Paraproteinemias (Monoclonal Gammopathy) 12/2012 - 03/2009
1	Vesicular Stomatitis 12/2020
1	Transthyretin-Related Hereditary Amyloidosis 11/2020
1	Plasma Cell Neoplasms 01/2020
1	Immunoproliferative Disorders 01/2017
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2017
1	Residual Neoplasm 01/2016
1	Cardiomyopathies (Cardiomyopathy) 01/2015
1	Autoimmune Diseases (Autoimmune Disease) 11/2014
1	Albuminuria 12/2012
1	Necrosis 12/2012
1	Kidney Diseases (Kidney Disease) 12/2012
1	Dementia (Dementias) 05/2012
1	Monoclonal Gammopathy of Undetermined Significance 01/2012
1	Disease Progression 09/2010
1	Hemolysis 08/2009
1	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2007

Drug/Important Bio-Agent (IBA)

30	Amyloid (Amyloid Fibrils)IBA 11/2020 - 07/2006
25	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2020 - 07/2006
20	Proteins (Proteins, Gene)FDA Link 06/2021 - 06/2008
5	Immunoglobulins (Immunoglobulin)IBA 02/2017 - 01/2008
2	Immunoglobulin M (IgM)IBA 01/2021 - 01/2020
2	AntigensIBA 12/2020 - 07/2007
2	GlycosaminoglycansIBA 02/2015 - 09/2011
2	PolyaminesIBA 08/2008 - 07/2007
2	Immunoglobulin FragmentsIBA 08/2008 - 07/2007
1	Cancer VaccinesIBA 12/2020
1	Neoplasm Antigens (Tumor Antigens)IBA 12/2020
1	Keratins (Keratin)IBA 11/2020
1	Complement System Proteins (Complement)IBA 11/2020
1	ProteomeIBA 11/2020
1	Contractile ProteinsIBA 11/2020
1	Amino Acids FDA Link 09/2018
1	florbetapirIBA 01/2017
1	Extracellular Matrix ProteinsIBA 01/2017
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2017
1	Peptides (Polypeptides)IBA 01/2016
1	AlbuminsIBA 12/2012
1	Glutamic Acid (Glutamate)FDA Link 05/2012
1	PolymersIBA 09/2011
1	Hemolysin Proteins (Hemolysins)IBA 08/2009
1	GadoliniumIBA 08/2008
1	gadolinium 1,4,7,10- tetraazacyclododecane- N,N',N'',N'''- tetraacetateIBA 08/2008
1	EmulsionsIBA 08/2008
1	Chelating AgentsIBA 08/2008
1	Contrast MediaIBA 07/2007
1	Radioisotopes (Radionuclides)IBA 07/2007
1	Monoclonal AntibodiesIBA 07/2007
1	Immunoglobulin G (IgG)IBA 07/2007
1	Tumor Suppressor Protein p53IBA 03/2007
1	PutrescineIBA 07/2006

Therapy/Procedure

2	Immunotherapy 01/2017 - 07/2007
2	Intravenous Injections 08/2008 - 07/2007
1	Aftercare (After-Treatment) 11/2013